🚨Exciting new press release in HR /HER2- breast cancer! Current standard of care for the past 20 years in early stage HR breast cancer has been endocrine therapy with tamoxifen or an aromatase inhibitor. In metastatic breast cancer, we are increasingly using oral SERDs, which are selective estrogen receptor degraders. SERDs work by binding to the estrogen receptor, which causes a conformational change that leads to the receptor’s degradation through the proteasome pathway. There are several SER
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🚨Exciting new press release in HR /HER2- breast cancer! Current sta…
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FacebookEleonora Teplinsky, MD
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Young patients with HR-positive, HER2-negative breast cancer are often treated with hormone therapy and chemotherapy and have a 2-3x increased risk of breast cancer recurrence over their lifetime. It is believed that targeted treatments in addition to chemotherapy could improve patient outcomes for young, early breast cancer patients. The OLIO clinical trial aims to find out if the addition of olaparib, or a combination of olaparib and durvalumab, given together with standard chemotherapy, can h
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