Although discrimination both by clinicians and by patients and families is relatively common in the United States, the laws that can be used to address these two types of discrimination differ subs ...

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-cell disorder present in approximately 5% of the general population over the age of 50 years. MGUS is characterized ...

Sotatercept, an activin-signaling inhibitor, reduces morbidity and mortality among patients with long-standing pulmonary arterial hypertension. Its effects in patients with pulmonary arterial ...

Bronchiectasis guidelines are inconsistent with regard to the effectiveness of mucoactive agents, and their use varies ...

In a patient with treatment-resistant ulcerative colitis, CD19 CAR T-cell therapy led to drug-free remission and mucosal healing, suggesting that B-cell targeting may offer a novel therapeutic pathway ...

The U.S. government has terminated grants funding work it considers to address “DEI,” conflating health equity research with efforts to change the composition and climate of the scientific workforce.

The epidemiology of tumor lysis syndrome is evolving with the introduction of newer therapies. The occurrence of tumor lysis syndrome has become a less predictable but increasingly important aspect of ...

Dr. Marcus L. Basiri (Pediatrics): An 11-year-old girl was transferred to the pediatric service of this hospital because of chest pain, arm pain, and multiple bone and liver lesions seen on imaging.

The painkilling, antipyretic, and antiinflammatory properties of aspirin have been known for centuries. The understanding that aspirin targets cyclooxygenase-1 (COX-1) (also known as ...

The scientific imperative to identify drugs that could repair mutant CFTR presented a formidable challenge. Small molecules that specifically bound and repaired a defective CFTR peptide fold were ...

Aortic dissection is a catastrophic event that affects approximately 13,000 persons each year in the United States. 1 Most patients with a type B aortic dissection, in which the origin of the aortic ...