Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit ...

Cells contain a DNA sensor called cGAS, which alerts the immune system to viral and bacterial infections, cell death, and cancer-related transformations. A research team led by Ikerbasque Research ...

Organelles in cells were originally often independent cells, which were incorporated by host cells and lost their ...

A research led by Sergio P. Acebrón, Researcher Ikerbasque at the UPV/EHU, develops a key tool to visualize the immune response to abnormal DNA, opening new avenues for the treatment of diseases.

The study, published in the prestigious journal EMBO Journal, reveals why some tumors escape the immune system, and offers a ...

Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education; Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical ...

Mitochondria evolved from an internalized bacterium, and most of the genes in the ancestral mitochondrial genome have moved into the cell’s nucleus 2. Human mitochondrial DNA (mtDNA) encodes ...

"Until a few years ago, we were sure that mitochondria produced ATP via oxidative phosphorylation in the intermembrane space, where the inner and outer membranes interact. This has changed.

Armed with inducible peroxide systems and fluorescent reporters, these scientists demonstrated that hydrogen peroxide produced at the mitochondria doesn’t adequately travel to the nucleus. The ...

“You start to realize that actually, to get from the mitochondria into the nucleus and damage the DNA, you have to pass a lot of stuff,” he said, adding that because of ROS’s reactivity, it would ...

Mitochondria are essential organelles for cell metabolism, growth, and function. Mitochondria in lung cells have important roles in regulating surfactant production, mucociliary function, mucus ...