Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Researchers at Kumamoto University have successfully executed a practical trial of a new genome-editing technique that allows ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Suffering on such an immense scale can appear hopeless. However, a technique called CRISPR gene editing promises to help deal with these issues and many more—and wise regulation can spur it on.

Department of Computer Science, University of New Mexico, Albuquerque, New Mexico 87131, United States Center for Biomedical Engineering, University of New Mexico, Albuquerque, New Mexico 87131, ...

In 2012, Jennifer Doudna and Emmanuelle Charpentier published their groundbreaking work, revealing that CRISPR/Cas9 could be re-engineered as a gene-editing tool. They won the Nobel Prize in ...

At the heart of this technology is the Cas9 protein, often likened to molecular ... where analytical chemistry and life science collide, CRISPR’s growing influence is unmistakable, taking ...

A proof-of-concept study shows that CRISPR-Cas9 can eliminate extra chromosome copies in Down syndrome cells. The method restores normal gene function but is not yet ready for human trials. Scientists ...