CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing.

The class II clustered regularly interspaced short palindromic repeats (CRISPR)–Cas systems, characterized by a single effector protein, can be further subdivided into types II, V, and VI. The ...

In this important work, the authors develop a theory for the coevolutionary dynamics of bacteria and phages, where the major evolutionary pressure comes from CRISPR-Cas adaptive immunity in bacteria.

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR associated (Cas) systems (i.e., CRISPR/Cas) have received significant credit in modern analytical science with the capability ...

Today we look at more moments from the Leader's image archive, featuring lots of memories. Do you recognise yourself? Don't forget to tag friends or family if you recognise them.

This month's cover highlights the article Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration by Helen Weavers and Tua Karling. The cover features confocal ...

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) /CRISPR-associated protein 9 (Cas 9) evolved naturally as a defence mechanism in bacteria and archaea. It was first reported in E.

A reality TV star broke down while looking at photos of herself, after feeling like she needed to get dangerous surgery due to public scrutiny. Chloe Ferry was 19 when she rose to fame on popular ...

1 At conferences like Pittcon, where analytical chemistry and life science collide, CRISPR’s growing influence ... with limited laboratory resources. 9 An expert in the design and development ...

(C through K) Representative light sheet microscopy scanning pictures of brains from ccm2 CRISPR adult zebrafish on Tg(fli1:EGFP) background. In controls without chemical treatment (C, D, and E) there ...

A proof-of-concept study shows that CRISPR-Cas9 can eliminate extra chromosome copies in Down syndrome cells. The method restores normal gene function but is not yet ready for human trials. Scientists ...