The totality of bacteria, viruses and fungi that exist in and on a multicellular organism forms its natural microbiome. The ...

It is well known that apoptosis is an actively mediated cell suicide process. In contrast, necrosis, a morphologically distinct form of cell death, has traditionally been regarded as passive and ...

Nucleotide-binding domain leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasome complex regulates the caspase-1 activity and subsequent processing of interleukin-1β (IL-1β).

Apoptosis, therefore, seems to be the most logical mechanism of cell death. In this Review, Narula et al. discuss the role of apoptosis in systolic dysfunction and heart failure, ...

In daf-2 and daf-16 mutant strains, baicalein demonstrated partial dependence on the IIS pathway for its protective effects. Conclusions:This study established a DSS-induced UC model in C. elegans and ...

Polyphenol-rich apple extracts have been reported to suppress human colon cancer cell growth in vitro. The protein kinase C (PKC) is among the signaling elements known to play an important role in ...

I decided that I, too, needed to attend the Longwood Area Worm Meeting. Thus began a trip into the world of C. elegans worms and the people who love them. In 25 years as a writer in Boston, I’ve ...

A computational approach is presented for modeling and quantifying the structure and dynamics of the nematode C. elegans observed by time-lapse microscopy. Worm shape and conformations are expressed ...