Spir proteins nucleate actin polymerization by assembling a linear actin oligomer along a cluster of four actin-binding WH2 domains, and this process is enhanced by formins of the Cappuccino family.

But Portnoy, who joined UPenn’s medical school in 1988, had found he could block this cell-to-cell spread by chemically inhibiting the polymerization of actin, a protein that cells use to build an ...

potentially promoting actin polymerization in a new direction. In the absence of SNX33, WAVE2 instead persisted at the site of contact, while actin filaments accumulated within the cell. These results ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

In this study, researchers investigated the adverse effects of QDs by focusing on actin depolymerization and polymerization, one of the most crucial cellular processes. Specifically, several ...

Prolonged morphine treatment increased the density of dendritic spines in wide dynamic range neurons in wildtype mice, and this was accompanied by evidence of actin filament polymerization in the ...