Gut

Impaired glucose metabolism in irritable bowel syndrome: personalised low-glycaemic diet as potential therapeutic target

We read with great interest the recent study by Gilliam-Vigh et al demonstrating significant transcriptomic alterations in ...
Gut

Response to: ‘Endoscopic intermuscular dissection for rectal cancer: are we ready to skip surgery?’ by Ichimasa et al

We would like to thank Dr Ichimasa and colleagues for their comments on our recent publication reporting the 3-year ...
Gut

FODMAPs and functional dyspepsia: emerging evidence but unanswered questions

Functional dyspepsia (FD) is a common disorder of gut-brain interaction (DGBI) characterised by symptoms of epigastric pain ...
gut.bmj

Alterations of gut microbiome in autoimmune hepatitis

Objective The significance of the liver-microbiome axis has been increasingly recognised as a major modulator of autoimmunity. The aim of this study was to take advantage of a large well-defined ...
gut.bmj

Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia–mesenchymal transition during pancreatic carcinogenesis

Objective SETD2, the sole histone H3K36 trimethyltransferase, is frequently mutated or deleted in human cancer, including pancreatic ductal adenocarcinoma (PDAC). However, whether SETD2/H3K36me3 ...
gut.bmj

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...
gut.bmj

Race-dependent association of sulfidogenic bacteria with colorectal cancer

3 Center for Clinical and Translational Science, University of Illinois at Chicago, Chicago, Illinois, USA 9 Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, ...
gut.bmj

Alterations in intestinal permeability

The goal of this review is to describe barrier function of the intestine, the structure of the tight junction, methods to evaluate intestinal permeability, and most importantly the relevance of ...
gut.bmj

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Objective In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed death ligand 1 ...
gut.bmj

Effect of bowel preparation and colonoscopy on post-procedure intestinal microbiota composition

1 Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Greenebaum Cancer Center, Baltimore, Maryland, USA 2 Division of Gastroenterology and Hepatology, ...
gut.bmj

Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease

Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, has multifactorial aetiology with complex interactions between genetic and environmental factors. Over 150 ...
gut.bmj

Bacteria as the cause of ulcerative colitis

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