Ryan Seacrest was facing a major challenge when he took over as the host of “Wheel of Fortune” from the legendary Pat Sajak.

Ryan Seacrest chuckled at a Wheel of Fortune contestant’s family who didn’t seem too excited that he was on the game show.

The long-time "Wheel of Fortune" co-host sat down for an interview with Elvis Duran, host of the "Elvis Duran and the Morning Show" on March 4 to talk all things "Wheel of Fortune," including ...