Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

The production and secretion of antibodies by human plasma cells (PCs) are two essential processes of humoral immunity. The secretion process relies on a group of proteins known as soluble ...

Bacterial type III secretion machines have adapted to carry out numerous functions, ranging from locomotion to protein delivery into nucleated cells. One of the most intriguing issues is the source of ...

The system that allows the sharing of genetic material between bacteria – and therefore the spread of antibiotic resistance – has been uncovered by a team of scientists at Birkbeck, University of ...

New research shows that a cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans. The findings ...

The proteins responsible for the control of mucin secretions, a key component of protective mucus, have been established in two recent papers. Mucins, the vital proteins that compose the protective ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

A cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans, new research shows. New research ...