November 16, 2009 (Orlando, Florida) — An analysis of the Heart Outcomes Prevention Evaluation (HOPE) study has potentially identified a new biomarker of renin angiotensin system (RAS) activation that ...

May 17, 2005 (San Francisco) - Patients with hypertension and high ambulatory plasma renin levels are at greater risk of myocardial infarction and revascularization procedures than those with low ...

Binding of renin to this receptor increases the catalytic activity of renin by about four- to fivefold. Furthermore, prorenin, which does not exhibit significant ability to generate angiotensin I (ang ...

OBJECTIVE: To evaluate the relationship between insulin, the renin-aldosterone system and blood pressure in obese subjects. The aim of this work was to study the relationship between insulin and the ...

Aliskiren is an orally active, nonpeptide, potent direct renin inhibitor that decreases plasma renin activity (PRA) and inhibits the conversion of angiotensinogen to angiotensin I. Unlike ACE ...

Assistant Professor of Medicine at Harvard Medical School and Associate Physician at Brigham and Women's Hospital, Division of Endocrinology Measurement of renin and its activity is increasingly used ...

To facilitate high throughput screening of renin inhibitors, we have developed new renin assay kits utilizing FRET peptide substrates. The SensoLyteTM 520 Renin Assay Kit contains FRET peptide labeled ...

Renin–angiotensin system (RAS) inhibitors — including angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) — slow the progression of mild or moderate chronic kidney ...

VANCOUVER, B.C.—High plasma renin activity (PRA) is associated with adverse renal outcomes in patients with coronary artery disease (CAD), according to study findings presented at the World Congress ...

Low pathologic complete response (pCR) rate to neoadjuvant chemotherapy in invasive lobular carcinoma of breast: Analysis of subgroup of four phase II trials This is an ASCO Meeting Abstract from the ...