When back pain flares up, you want fast, effective relief. So you open your medicine cabinet in search of pain medicine and then it hits you: Which over-the-counter (OTC) painkillers are actually best ...

This story was originally published on April 18, 2025, and has been updated. When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or non-steroidal ...

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Millions of Americans take over-the-counter pain meds, but many don't understand how they work or the risks involved in taking them. We look at best practices for taking non-prescription pain drugs.