Discover 8 ways mast cell activation syndrome causes widespread symptoms from digestive issues to brain fog, often mistaken ...

Mast cell activation syndrome (MCAS) is a condition in which mast cells—a type of white blood cell that plays a key role in ...

The following is a summary of “Novel Bradykinin Detection In The Diagnostic Workup Of Patients With Recurrent Angioedema ...

This process, known as degranulation, is essential for protection against threats such as bee venom, snake bites and pathogenic bacteria, but erroneous activation of mast cells also triggers ...

Mast cells, particularly the MCTC subtype found in the skin, are central to the pathogenesis of CSU. Their activation occurs via immunoglobulin E (IgE)-dependent receptors as well as via other ...

Caroline Cray was diagnosed with mast cell activation syndrome in May 2019 after repeated anaphylactic episodes Jordan Greene is Society and Culture writer-reporter at PEOPLE. She has been working ...

At the recent AAAAI/WAO meeting, Blueprint Medicines Corp. presented the in vitro and in vivo characterization of BLU-808, a selective inhibitor of wild-type KIT, a transmembrane receptor tyrosine ...

CDX-622 inhibits SCF and TSLP-dependent inflammatory signatures in human skin -- Phase 1 study in healthy volunteers ongoing -HAMPTON, N.J., ...

Mice without MrgprA3 showed no itch sensation and failed to develop an inflammatory response, including neutrophil infiltration and mast cell activation, when exposed to allergens. The same ...