When designing microscopes, optical engineers have long faced a trade-off between speed, field of view and resolution. But ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Advances in the ability to image cells and tissues have driven progress in cell and developmental biology, among other fields. Current developments in light microscopy research include volumetric and ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

During image analysis, researchers use light sheet microscopy of cleared tissue as a preferred method for high throughput volumetric imaging. A flexible system can provide a range of sizes, resolution ...

Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, ...

With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments. As a mouse explores its ...

Modern imaging is contributing significantly to giving us a better understanding of how our brains work. In the long term, this will also help us to treat learning disorders in a more targeted way and ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Key to understanding something like epilepsy is to be able to record highly transient events in biological tissues. Generally ...

In this episode of C&EN Uncovered, host Craig Bettenhausen speaks with C&EN senior editor Laurel Oldach about a laser phase ...