The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.
Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, No. 1, [Part 2: Biological Sciences] (Jan., 1981), pp. 524-528 (5 pages) Several biological effector functions ...
Nipocalimab is the first FcRn blocker approved in both adult and adolescent gMG patients aged 12 and older who are anti-AChR or anti-MuSK antibody-positive In the pivotal Phase 3 Vivacity-MG3 and ...
IgG subclasses differ in their effector functions in a variety of in vitro assays. To assess the effect of antibody subclass differences on in vivo protective efficacy against herpes simplex virus ...
An international research group directed by UMC Utrecht has developed and characterized two first-in-class antibodies that ...
Two new antibodies may treat autoimmune diseases by reducing inflammation through blocking the immune receptor FcγRI.
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