Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called ...

Understanding how to control stem cell differentiation has been a pivotal pursuit in biomedical research. Recent findings highlight the significant role of RNA condensates, particularly P-bodies, in ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

A research team at the Max Planck Institute for Chemical Ecology has successfully combined single-cell RNA sequencing (scRNA-seq) and single-cell mass spectrometry (scMS) analysis on the same plant ...

Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

The cell and gene therapy industry has achieved breakthroughs once thought impossible, translating novel concepts into real therapeutic options for patients. The FDA has now approved 43 cell and gene ...

The study reveals how hair pigment stem cells respond to DNA damage by making fate decisions that can result in either hair graying or the development of melanoma. Throughout life, our cells face ...

Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better drugs for this psychiatric disorder. To test this hypothesis, Girgenti and his ...

Japanese researchers discovered that hair graying and melanoma share a surprising cellular origin. When DNA damage strikes melanocyte stem cells, they may undergo a protective process called ...