Precise control of sodium excretion by the kidney is critical for maintaining fluid and electrolyte homeostasis. A new mouse model provides compelling evidence that a kinase, WNK4, provides key ...
The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers on all aspects of cellular structure and function ...
Renal Tubular Acidosis and Renal Potassium Wasting Acquired as a Result of Hypercalcemic Nephropathy
THE earliest lesions of certain types of experimental nephrocalcinosis involve the distal portions of the renal tubules and the collecting ducts. 1,2 Disturbances in renal tubular function might ...
Glucagon-sensitive adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity was measured in nine different portions of the rat nephron. Each sample contained a single piece of ...
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