Conversion from the asexual to the sexual phase of the malaria parasite is necessary for its transmission to the mosquito. A study led by the Barcelona Institute for Global Health (ISGlobal) -- an ...

Metabolism is known for its intricate adjustments to meet the needs of an organism. Due to demands of adaptation, parasite metabolic pathways are greatly altered from those of their hosts. A key ...

Un nouveau candidat vaccin bloque la transmission du paludisme chez les adultes. Deux gènes exprimés chez des adultes ghanéens, qui perturbent le cycle de vie du plasmodium falciparum, offrent de ...

Plasmodium falciparum causes malaria in humans by multiplying first in the liver cells and then in red blood cells. Merozoites or daughter parasites are released as the host cells are destroyed to ...

Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

The 6 enzymes involved in de novo synthesis of pyrimidines were measured in Plasmodium falciparum isolated by saponin lysis from RBC's nonsynchronized and synchronized in vitro cultures. The total ...

Des revues scientifiques révèlent que des modifications génétiques de parasites propagés par les moustiques pourraient transformer les piqûres d’insectes en autant d’injections de vaccin. Les premiers ...