High-pressure homogenization is a powerful technique that can rapidly break apart stubborn cells, for example, by limiting the number of passes needed to disrupt them. The cooling available in a ...

In Naviaux’s framing, extracellular ATP acts as a danger signal that keeps cells in that defensive mode. If the signal stays ...

Viruses are masters at taking over our cells: They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes ...

Microscopy image of a human stem cell-derived hippocampal organoid. When the tissue carries an epilepsy-causing variant in the SCN8A gene, inhibitory neurons (seen in red) are disrupted, and ...