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28. Martino AT, Basner-Tschakarjan E, Markusic DM, et al. Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells. Blood 2013; 121: 2224–2233. 29.
Yu: We have so many opportunities, not only treating rare diseases with AAV but also many common diseases like diabetes, Alzheimer’s, aging, and even COVID-19. Replacing the gene of interest and ...
AAV Vectors AAVs are single-stranded DNA viruses that require co-infection with other viruses, mainly adenoviruses, to replicate. When used as gene therapy vehicles, researchers generate recombinant ...